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Oncology
Pancreatic Cancer: Review Questions
N. Joseph Espat, MD
Dr. Espat is an Assistant Professor of Surgery, Department of
Surgery, University of Illinois at Chicago, Chicago, IL.
Choose the single best answer for each question.
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1. Approximately how many cases of pancreatic adenocarcinoma occur
in the United States annually?
- 30,000
- 50,000
- 75,000
- 90,000
- 150,000
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2. Which of the following statements regarding pancreatic
adenocarcinoma is INCORRECT?
- Survival beyond 2 years following diagnosis is uncommon
- The majority of affected patients have surgically resectable tumors
- The majority of tumors arise in the head of the pancreas
- The median age of affected patients is 60 to 70 years
- The most frequent presentation of the disease is painless obstructive jaundice
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3. A previously healthy 65-year-old man with painless obstructive jaundice
visits his physician. As part of his work-up, the patient undergoes a computed
tomographic (CT) scan of the abdomen. Results show that the distal common bile
duct and pancreatic ducts are dilated; a discrete 2.5-cm mass is seen in the
head of the gland, along with a 3-cm segment of involved portal vein. No
evidence of metastases is observed. Based on current staging guidelines
from the American Joint Committee on Cancer, which of the following clinical
stages best describes this patients cancer?
- Stage I
- Stage II
- Stage III
- Stage IVA
- Stage IVB
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4. Which of the following procedures provides the most accurate prelaparotomy
staging of patients with pancreatic cancer?
- Abdominal ultrasonography
- CT scan and laparoscopy
- CT scan and magnetic resonance imaging (MRI)
- Endoscopic retrograde cholangiopancreatography (ERCP) and CT scan
- ERCP and MRI
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5. Which of the following is the recommended drug or combination of drugs
for treatment of patients with locally advanced or metastatic unresectable
pancreatic adenocarcinoma?
- 5-Fluorouracil
- 5-Fluorouracil and leucovorin
- 5-Fluorouracil and mitomycin
- Gemcitabine
- Gemcitabine and leucovorin
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