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Neurology
Neurosarcoidosis: Review Questions
Bertrand C. Liang, MD
Dr. Liang is Adjunct Associate Professor of Medicine and Neurology, University of Vermont College of Medicine, Burlington, VT, and a member of the Hospital Physician Editorial Board.
Choose the single best answer for each question.
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1. Neurosarcoidosis most often involves which of the following structures of the nervous system?
- Muscle
- Meninges
- Cerebellum
- Cortex
- Peripheral nerve
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2. A tissue sample positive for neurosarcoidosis exhibits nodules composed of all of the following cell types EXCEPT:
- Astrocytes
- Lymphocytes
- Endothelial cells
- Giant cells
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3. The cranial nerve most frequently involved in neurosarcoidosis is:
- VII
- III
- II
- IV
- I
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4. All of the following are neurosarcoid-associated syndromes EXCEPT:
- Aseptic meningitis
- Diffuse encephalopathy with vasculopathy
- Amyloidosis
- Seizures
- Hypothalamic syndrome
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5. All of the following laboratory data are supportive of sarcoidosis EXCEPT:
- Increased serum globin levels
- Increased serum calcium levels
- Increased serum/cerebrospinal fluid angiotensin converting enzyme (ACE) levels
- Positive skin-tuberculin reaction
- Increased glycol-precipitable immunoglobulin levels
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6. Which of the following choices best describes how the diagnosis of neurosarcoidosis is made?
- Clinically
- By a history of cranial neuropathy and an elevated ACE level in serum
- By confirmatory biopsy of a nodule and a history of neurologic signs or symptoms
- Only at autopsy
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7. The differential diagnosis of neurosarcoidosis includes all of the following EXCEPT:
- Hodgkins lymphoma
- Non-Hodgkins lymphoma
- Syphilis
- Multiple sclerosis
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